Cartilage Hair Hypoplasia with Thrombocytopenic Purpura, Autoimmune Haemolytic Anaemia and Cell-Mediated Immunodeficiency

Thrombocytopenic purpura in patient with autoimmune haemolytic anaemia, successfully treated with mercaptopurine.

[The effectiveness of rituximab in refractory autoimmune thrombocytopenic purpura and haemolytic anaemia].

OBJECTIVE To evaluate the efficacy and safety of treatment with rituximab in patients presenting autoimmune thrombocytopenic purpura and haemolytic anaemia. METHOD A check was carried out of the medical records of the patients starting treatment with rituximab for compassionate use in 2004 at doses of 375 mg/m2 per week for 4 weeks. The rate of patients achieving full response in accordance w...

A rare case of autoimmune hepatitis overlapping with autoimmune haemolytic anaemia and immune thrombocytopenic purpura in a male patient.

Med J Malaysia Vol 67 No 3 June 2012 INTRODUCTION Autoimmune hepatitis (AIH), which predominantly affects women and usually responds to immunosuppressive therapy, is a disease characterized by hypergammaglobulinemia, increased titers of serum tissue autoantibody, and an immunogenetic background. This disease can present with a variety of coexisting non-hepatic disorders presumably caused by imm...

Purpura fulminans with haemolytic anaemia.

A 10-month-old female infant with purpura fulminans is reported. The patient had clotting abnormality compatible with consumption coagulopathy. Histopathological examination revealed the presence of microthrombi. Heparin was effective in correcting the clotting defects. The infant also suffered from microangiopathic haemolytic anaemia. She died 17 days after the onset of the illness from infect...

Cartilage Hair Hypoplasia: First report from Iran

  Cartilage hair hypoplasia (CHH), is a rare cause of metaphyseal chondrodysplasia and short stature. Other features included hair abnormality, immunodeficiency, anemia, gastrointestinal disorders (Hirschsprung disease, celiac, …) and increased risk of cancer. The disease is an autosomal recessive disorder and previously has not been reported in Iran. We report a 9-year-old boy diagnosed as car...